GDF15

GDF15 - Wikipedia

Growth/differentiation factor 15 (GDF15) was first identified as Macrophage inhibitory cytokine-1 or MIC-1. It is a protein belonging to the transforming growth  ...

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GDF15 Gene - GeneCards | GDF15 Protein | GDF15 Antibody

Complete information for GDF15 gene (Protein Coding), Growth Differentiation Factor 15, including: function, proteins, disorders, pathways, orthologs, and ...

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GDF15

27 Jan 2020 ... Results showed that GDF15, produced by senescent endothelial cells (ECs), improves adult blood-endothelial colony forming cells proliferation ...

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GDF15 mediates the effects of metformin on body weight and energy ...

25 Dec 2019 ... The correlation of GDF15 increment with changes in body weight, while statistically significant, was modest in size. Although we believe that it ...

gdf15

Gdf15

13 Jan 2020 ... Gdf15 growth differentiation factor 15 [ (house mouse)] ... osteocyte GDF15 stimulates prostate cancer growth and invasion and is related to ...

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GDF15 - Growth/differentiation factor 15 precursor - Homo sapiens ...

Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, ...

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GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular ...

Growth differentiation factor-15 (GDF-15) is a stress responsive cytokine. It is highly expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells,  ...

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GROWTH/DIFFERENTIATION FACTOR 15; GDF15

GDF15 is a distant member of the bone morphogenetic protein (BMP; see 112264) subfamily of the transforming growth factor-beta (see TGFB1; 190180) ...

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GDF15 and Growth Control | Physiology - Frontiers

27 Nov 2019 ... Growth/differentiation factor-15 (GDF-15) is a distant member of the transforming growth factor β (TGF-β) superfamily and is widely expressed in ...

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GDF15 gene - Genetics Home Reference - NIH

11 Feb 2020 ... From NCBI Gene: This gene encodes a secreted ligand of the TGF-beta ( transforming growth factor-beta) superfamily of proteins. Ligands of ...

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Gdf15 MGI Mouse Gene Detail - MGI:1346047 - growth ...

View mouse Gdf15 Chr8:70629393-70632456 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.

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GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice ...

10 Jan 2019 ... INTRODUCTION. GDF15 (growth differentiation factor 15; also known as macro- phage inhibitory cytokine-1 [MIC-1], NAG1, PLAB, and PDF) is.

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Evaluation of GDF15 as a therapeutic target of cardiometabolic ...

Growth differentiation factor 15 (GDF15) is a key regulator of body weight in animals by regulating food intake. Its receptor, glial cell-derived neurotrophic factor ...

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GDF15 gene homepage - Global Variome shared LOVD

3 May 2013 ... General information. Gene symbol, GDF15. Gene name, growth differentiation factor 15. Chromosome, 19. Chromosomal band, p13.11.

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Gene: GDF15 (ENSG00000130513) - Summary - Homo sapiens ...

Gene: GDF15 ENSG00000130513 . twitter logo Twitter facebook logo Facebook email logo Email. Description. growth differentiation factor 15 [Source:HGNC ...

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Growth differentiation factor 15 is a myomitokine governing systemic ...

16 Dec 2019 ... GDF15 expression is regulated by various transcriptional pathways, dependent on the cellular and signaling context (Ago and Sadoshima, ...

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TGF-β contamination of purified recombinant GDF15

21 Nov 2019 ... GDF15 is a stress-activated cytokine that during physiological conditions only is found at high levels in the placenta.[2] Elevated serum levels of ...

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GDF15 maturation requires proteolytic cleavage by PCSK3, 5 and 6

13 Aug 2019 ... Growth differentiation factor 15 (GDF15) is a secreted protein with pleotropic ... undergoes proteolytic cleavage to generate mature GDF15.

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GDF15 promotes the proliferation of cervical cancer cells by ...

10 Apr 2019 ... Growth differentiation factor 15 (GDF15) is a member of the TGF-β superfamily, and evidence suggests that a substantial amount of GDF15 is ...

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GDF15 - Clinical: Growth Differentiation Factor 15 (GDF15), Plasma

GDF15 : Mitochondria perform many important metabolic functions, the most vital being the production of energy in the form of adenosine triphosphate (ATP) ...

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Local and systemic pro-tumorigenic effects of fibroblast-derived ...

29 Apr 2014 ... Local and systemic pro-tumorigenic effects of fibroblast-derived GDF15/MIC-1. Francesca Bruzzese, Christina Hagglof, Alessandra Leone, Elin ...

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Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from ...

18 Oct 2019 ... GDF15 was identified as a highly up-regulated gene in the liver and fat of ob/ob mice in a microarray study to identify secreted proteins that ...

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Exercise training promotes a GDF15-associated reduction in fat ...

24 Apr 2019 ... Growth differentiation factor 15 (GDF15) has shown promise as a weight loss agent for obesity in animal studies. In healthy lean humans, fastin.

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Growth Differentiation Factor 15 (GDF15), Plasma - Mayo Clinic ...

Specimen Required. Container/Tube: Preferred: Lavender top (EDTA) plasma. Acceptable: Green top (sodium heparin) plasma. Submission Container/Tube: ...

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GDF15, a Cardioprotective TGF-β Superfamily Protein | Circulation ...

17 Feb 2006 ... GDF15/MIC-1 functions as a protective and antihypertrophic factor released from the myocardium in association with SMAD protein activation.

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Gdf15 regulates murine stress erythroid progenitor proliferation and ...

19 Jul 2019 ... Gdf15−/− mice fail to expand stress erythroid progenitors in response to anemic stress, in part because of defects in the splenic niche. Gdf15 ...

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Gene: GDF15 (ENSG00000130513) - Summary - Homo sapiens ...

Annotation for this gene includes both automatic annotation from Ensembl and Havana manual curation, see article. Annotation Attributes. ncRNA host ...

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Cleavage of growth differentiation factor 15 (GDF15) by membrane ...

Growth differentiation factor 15 (GDF15), a transforming growth factor (TGF)-β superfamily member, has been cloned from a placenta. cDNA library as a gene ...

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GDF15 (growth differentiation factor 15)

GDF15 (growth differentiation factor 15), Authors: Shantibhusan Senapati, Ajay P Singh, Surinder K Batra. Published in: Atlas Genet Cytogenet Oncol Haematol.

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Circulating levels of GDF15 in patients with myalgic ...

4 Dec 2019 ... Circulating GDF15 remained stable in a subset of ME/CFS patients when sampled on two occasions ~ 7 months (IQR 6.7–8.8) apart, 720 pg/ml ...

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Mouse/Rat GDF-15 Quantikine ELISA Kit MGD150: R&D Systems

The Quantikine Mouse/Rat GDF-15 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse and rat GDF-15 in cell culture supernates, serum ...

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GDF15 ELISA Kits | Biocompare.com

393 products ... The ELISA kits listed below target GDF15, the symbol for the human gene, growth differentiation factor 15, and a member of the TGF-beta family.

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IL‑17A and GDF15 are able to induce epithelial‑mesenchymal ...

10 May 2019 ... The aim of the present study was to investigate the role of IL‑17A and GDF15 in the pathogenesis of COPD. It was demonstrated that IL‑17A ...

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GDF15 Human ELISA Kit - Invitrogen

GDF15 Human ELISA Kit from Invitrogen (96 tests). Quantitate human GDF15 in supernatant, plasma and serum. Sensitivity: 2 pg/mL.

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GDF15 reduces development of type 1 diabetes in mice

10 Jan 2020 ... Researchers have discovered that type 1 diabetes patients have low levels of growth differentiation factor 15 (GDF15) in their pancreatic β cells ...

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NF-κB regulates GDF-15 to suppress macrophage surveillance ... - JCI

11 Sep 2019 ... Macrophages are attracted to developing tumors and can participate in immune surveillance to eliminate neoplastic cells. In response ...

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The effect of GDF15 on the neurite outgrowth in retinal ganglion cells.

Purpose : Growth differentiation factor 15 (GDF15) is reported to be increased in mouse retina after optic nerve crush and in aqueous humor of primary open ...

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MIC-1/GDF15 Overexpression Is Associated with Increased ...

2 Dec 2019 ... Abstract Spinal cord injury (SCI) has devastating consequences, with limited therapeutic options; therefore, improving its functional outcome is ...

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GDF15 Concentrations in Maternal Serum Associated with Vomiting ...

17 Nov 2019 ... Growth and Differentiation Factor 15 (GDF15), secreted from the trophoblast and decidual stromal cells, is present at high levels in the blood of ...

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Anti-GDF15 antibody (HRP) (ab106260) | Abcam

Rabbit polyclonal GDF15 antibody conjugated to HRP. Validated in WB, ELISA and tested in Mouse, Human. Immunogen corresponding to synthetic peptide.

gdf15

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